| Skin Absorption: In Vivo Method (OECD TG 427) |
Skin Absorption: In Vitro Method Description and references |
OECD: Endorsed as equivalent to validated (2002) |
OECD: TG 428
EU: Regulatory accepted as dermal percutaneous absorption test for the REACH program in place of in vivo animal studies (2008) |
Replacement (When human skin is used)
OR
Reduction and Refinement (When skin from humanely killed animals is used)
|
May 2012 |