Step-by-Step Search Guide

• Step 3: Conduct first phase of search

The first phase is a broad search of both subject-specific information and Three Rs information, with more emphasis on Replacement alternatives. Objectives of the first phase are to:

  1. determine if the proposed experiment or test is duplicative
  2. search specifically for Replacement alternatives (such as less sentient or non-animal methods)
  3. find information about similar scientific uses of animals (which may provide information about possible alternatives, appropriate animal numbers, and what variability to expect)
  4. search for information that substantiates the choice of animal model